Acalabrutinib (ACP-196)

  • ₹ 14,445
  • 5 mg
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Product Details

  • Delivery Timeline
    Delivered within 2-3 weeks period
  • ID
    CH-xQC7Y3F
  • CAS Number
  • Sub Category
    Small Molecule Libraries
  • Expiry Date
    17-Nov-2024
  • Purity Percentage
    95
  • State
    Solid
  • Country
    India
  • City
    Hyderabad
  • Certified By
    NONE

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COA or MSDS Details

Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.